Simparica TRIO is an all-in-one monthly chewable for extra-large dogs (40-60kg) that prevents heartworm disease, treats and prevents fleas and ticks, and treats and controls roundworms and hookworms, in a single flavoured tablet.
Composition: Each tablet provides a minimum of 1.2mg/kg Sarolaner, 24mcg/kg Moxidectin, and 5mg/kg Pyrantel (as pamoate salt) - for this weight band, approximately 72mg Sarolaner, 1.44mg Moxidectin, and 300mg Pyrantel.
Indications: Prevention of heartworm disease; treatment and prevention of flea infestations; prevention of tapeworm via flea control; treatment and control of several tick species; treatment and control of roundworms and hookworms.
Dosage: One chewable tablet once a month, matched to the dog's 40-60kg weight band. Dogs over 60kg require a vet-directed combination of tablet strengths.
Directions for Use: Can be given with or without food. Ensure the dog consumes the entire tablet.
How does the medicine work?: Sarolaner kills fleas and ticks by overstimulating their nervous system; moxidectin prevents heartworm larvae from developing into adults; pyrantel paralyses and expels roundworms and hookworms - together covering five major parasite threats in one monthly dose.
Possible side effects: Isoxazoline-class drugs have been associated with neurologic adverse reactions such as tremors, ataxia and seizures - use with caution in dogs with a history of seizures.